The small Anzano is one of the last Apulian outposts on the border with Campania, so close to it to have been for a few decades Irpinia.
The village would have risen on a road junction of Roman times, at the intersection of the Via Erculea and the Via Aurelia Haeclanensis, which headed to Herdonias (Ordona).
For this position, according to some scholars, it is the place where it was actually located the famous taberna of villa trevici, where Horace stayed on his journey from Rome to Brindisi( 20 BC). Its coat of arms depicts a Roman temple crossed by a road.
Today it is presented with a blanket of red roofs, gently laid on a slope. The houses seem designed and the alleys are intertwined with tiny squares and characteristic steep staircases. The Marian Shrine is still the fulcrum of the town.
The modest extent of its territory is entirely flanked by the Tratturo Regio "Pescasseroli-Candela".