The church, dating from the first half of the 16th century, is also known as the Greek Rite Chapel, because it was originally built on the initiative of Antonio II Piccolomini to allow the Albanians of Deliceto to practice the liturgy according to the orthodox canons.
The simplicity and grace of the stone exterior is reflected in the small interior space, adorned only by a small altar leaning against the wall and a picture of the Madonna and Child; there are therefore no images of the Madonna of Loreto. Next to the church stood a small hospital, used to give comfort to the sick and as a place of rest and shelter for faithful and pilgrims; it was enlarged in the seventeenth century by Canon Bartolomeo Ciardi and remained in operation until the second half of the nineteenth century.
Below the level of the road that flanks it (Via Fontanelle), we find the old ossuary, with the remains of the victims of the plague that decimated the population of Deliceto in the sixteenth century. Not far away stands the only medieval access to the village that survived in time: Porta Scarano.