The name of the City could derive from the Indo-European term Ausa (source) and from Satricum, or from the name of an aromatic herb, the santoreggia (Satureja). The town retains traces of the Daunian-Roman and medieval ages; it was certainly an important Italic center, which had its own currency with the inscription Auhuscli. It was the scene of important historical events, such as the legendary Pyrrhic Victory of 279 BC.
Its surroundings are a real open-air museum, with important sites such as the Archaeological Park of the Dauni, the Monumental Area of the Snake, The Roman Villa of Faragola.
The historic center, on which the beautiful Palazzo Ducale watches, is a succession of houses, shops and palaces, which are located in a maze of alleys and medieval squares.
Ascoli is also rich in fascinating religious architecture, such as the Cathedral dedicated to the Nativity of the Virgin in Roman-Gothic style and the church with a convent dedicated to the patron saint, San Potito Martire. The unmissable symbol of the city, consisting of the sculptural complex of the Grifoni, is preserved, along with many other wonders in the Polo Museale "Pasquale Rosario".